INTRAUTERINE INSEMINATION

The term "IntraUterine Insemination" (IUI) refers to a technique consisting in a treatment of seminal fluid its injection into the uterine cavity. IUI is a “first level technique” carried out simultaneously with ovarian stimulation.

IUI is employed both for male and female infertility. Male causes requiring IUI are light oligoastenozoospermia, ipospermia, retrograde ejaculation, impotence, azoospermia (using sperm of a donor).
Feminine indications are infertility from cervical causes, minimal endometriosis.
IUI is less invasive and expensive than other assisted–reproduction techniques and can be easily performed.

To stimulate ovulation we usually use drugs (citrate clomiphene and gonadotropine). Dispensation starts during follicular phase and go on until diagnostic tests (ultrasound scan and hormone test) prove that the patient is ready for the insemination.

IUI is an out-patient treatment. A speculum is introduced into vagina then seminal fluid is slowly injected by a plastic catheter. A few minutes later, the patient can come back home.
IUI can pose some risks as multiple pregnancies, ovarian- hyperstimulation syndrome, spontaneous abortion, pelvic infection, uterine contractions and spasms, outbreak of antibody- anti-spermatozoa.
The rate of successful pregnancies is about 10%.

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